Use of orthogonal protecting groups (TBDMS and PMB) in combination with a two directional glycosylation strategy led to a convergent synthesis of two alternative repeating units of peptidoglycan.
Graphical Abstract
An intramolecular transition metal catalyzed carbometalation/capture sequence permits the stereoselective construction of the (bis)exocyclic dienyl subunit critical to the synthesis of Vitamin D and structural analogues.